Libido & Sexual Health

A foundational androgen reference entry. FDA-Approved for Confirmed Hypogonadism. Schedule III Controlled Substance. WADA S1 Absolute Ban. TRAVERSE Trial (NEJM 2023): TRT Does Not Increase Cardiovascular Events in Hypogonadal Men. The TTrials: Sexual Function, Bone Density, Anemia All Improved. The Central Paradox: The Compound That Is Appropriate Medical Treatment at One Baseline Testosterone Level Is Misuse at Another. Aromatization, Estradiol Management, HPTA Suppression, Testicular Atrophy, Fertility, and the Full Monitoring Protocol.

The Pure Active Isomer in Clomid. The Drug That Raised Testosterone as Well as TRT While Preserving Fertility — and Still Failed FDA Approval. The Zuclomiphene Problem: Why the Racemic Mixture Causes Side Effects Pure Enclomiphene Shouldn't. The NDA That Died in 2021. How It Differs from TRT, HCG, and Gonadorelin for Male Hypogonadism. The 2025 Meta-Analysis: +273 ng/dL Testosterone vs Placebo.

The Nobel Prize Decapeptide (Schally and Guillemin, 1977). The Compound That Is Stimulatory When Pulsatile and Suppressive When Continuous — From the Same Receptor. The Most Pharmacologically Nuanced Chapter in this reference. Why the FDA's March 2020 HCG Compounding Ban Changed TRT Practice Overnight. Gonadorelin vs HCG: The Fertility Preservation Head-to-Head. Why FSH Matters for Spermatogenesis. The Pulsatile Dosing Problem in Practice.

FDA-Approved for Fertility and Male Hypogonadism. The Most Important Hormone in Post-Cycle Therapy. The Active Ingredient in the Simeons 500-Calorie Diet — a Fraud With Its Own FDA Warning. WADA S2 Banned. A Tumor Marker. Three Completely Different Identities in One Glycoprotein.

Named After Hershey's Kisses. Discovered as a Metastasis Suppressor Gene. Repurposed as the Master Upstream Regulator of the Entire HPG Axis. The Most Potent Known Activator of GnRH Neurons. Human Clinical Trials in Hypogonadotropic Hypogonadism, Hypothalamic Amenorrhea, IVF Triggering, and Hypoactive Sexual Desire Disorder. Limbic Brain Activation Proven by fMRI. No FDA Approval. The Most Pharmacologically Compelling Compound in PCT That No One Has Properly Studied for PCT.

Amino-acid-derived quaternary ammonium compound involved in mitochondrial fatty-acid transport. Commercial claims are often overstated, but specific forms have clinical evidence for neuropathy, peripheral artery disease, muscle recovery, male infertility, and post-MI cardiac outcomes.

One Molecule That Tans Your Skin, Triggers Erections, Suppresses Appetite, and Elevates Blood Pressure — All Through Different Receptors on the Same Injection. The University of Arizona Drug That Spawned PT-141. Why the 'Barbie Drug' TikTok Trend Is the Most Dangerous Community Use Pattern in this reference. The Melanoma Question: Four Case Reports, Two Conflicting Reviews, and One Confound. Rhabdomyolysis at 12x the Starting Dose. What the Nasal Spray Market Actually Contains.

The First Peptide Ever Synthesized (Nobel Prize 1955). FDA-Approved for Obstetric Use Since the 1950s. The 'Love Hormone' That Science Has Substantially Complicated. Intranasal Bioavailability ~2%. Trust Enhancement Replication Failures. Autism Trials: Mixed to Null. Context-Dependent Effects That Can Go Either Direction. And an OTC Nasal Spray Industry Built on Evidence That Doesn't Support What It Claims.

Melanocortin receptor agonist used for desire/arousal signaling, with FDA-approved bremelanotide evidence and common nausea/flushing limits.