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Category

Longevity & Anti-aging

Compounds that target hallmarks of aging.

6 compounds tagged with longevity & anti-aging.

Rapamycin

mTOR inhibitor
B

mTORC1 inhibitor with the strongest longevity evidence of any pharmacologic in mammals.

Limited human data
Longevity
🚫Cancer cautionβœ“FDA-approved

Tesamorelin

GHRH analog
B

Long-acting GHRH analog approved for HIV lipodystrophy; off-label use for body composition and visceral fat.

Limited human data
MuscleLongevity
🚫Cancer cautionβ›”WADA S2βœ“FDA-approved

Testosterone / TRT

Steroid
A

Hormone replacement for hypogonadal men; widely used off-label for performance and body composition.

Strong human RCT
HormonalMuscleLongevity
🚫Cancer: hard stopβ›”WADA S1βœ“FDA-approved

Epithalon

Bioregulator
D

Tetrapeptide bioregulator from the Khavinson group; telomerase activation and lifespan claims rest mostly on Russian-language preclinical work.

In vitro / mechanistic
LongevitySleep
🚫Cancer caution⚠Single-lab

MOTS-c

Peptide
C

Mitochondrial-derived peptide with metabolic and exercise-mimetic effects in animal models.

Animal replicated
MitochondrialLongevity

NAD+/NMN

NAD+ precursor
C

NAD+ precursor supplement; raises blood NAD+ levels reliably but functional benefits in humans remain unclear.

Animal replicated
LongevityMitochondrial
🚫Cancer cautionβœ“Human RCTs
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