Cardarine
Research chemical · Grade C
Goals
muscle, weight-loss, mitochondria
Evidence
3 RCT / 5 animal / 3 in vitro
Half-life
Half-life in humans: approximately 16-24 hours, supporting once-daily dosing
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
5-Amino-1MQ
Research chemical · Grade C
Goals
muscle, weight-loss, mitochondria
Evidence
0 RCT / 4 animal / 3 in vitro
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
SLU-PP-332
Research chemical · Grade C
Goals
muscle, weight-loss, mitochondria
Evidence
0 RCT / 6 animal / 2 in vitro
Half-life
The compound also had sufficient pharmacokinetic properties (oral bioavailability ~45% in rodents, half-life ~8-10 hours) to work as an in vivo tool — it could be given orally t…
Primary mechanism
Activates all three estrogen-related receptors (ERRα, ERRβ, ERRγ) with highest potency for ERRα (EC50 = 98 nM).
ATX-304
Research chemical · Grade C
Goals
weight-loss, mitochondria
Evidence
1 RCT / 6 animal / 3 in vitro
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.