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Compound comparison

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GHRP-2

Research chemical · Grade C

Goals
muscle, sleep
Evidence
—
Routes
injectable-sc
WADA
S2
FDA
Not approved
Cancer caution
hard-stop
Typical dose
—
Half-life
Plasma half-life: approximately 15-30 minutes following subcutaneous injection
Primary mechanism
GHS-R1a agonism on pituitary somatotrophs → Gq/11 → PLC → IP3 + DAG → intracellular calcium release → PKC activation → GH vesicle exocytosis.
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CIT Stack

Research chemical · Grade C

Goals
muscle, sleep, weight-loss
Evidence
0 RCT / 0 animal / 0 in vitro
Routes
injectable-sc
WADA
S2
FDA
Not approved
Cancer caution
caution
Typical dose
—
Half-life
The CIT Blend uses CJC-1295 WITHOUT DAC (also called Mod GRF 1-29) — the pulsatile form with ~30 min half-life
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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CJC-1295 (no-DAC)

Research chemical · Grade C

Goals
muscle, sleep
Evidence
—
Routes
injectable-sc
WADA
S2
FDA
Not approved
Cancer caution
caution
Typical dose
—
Half-life
These four changes extend the plasma half-life from 4-7 minutes to approximately 30 minutes without meaningfully changing GHRH receptor binding affinity
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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CJC-1295 + Ipamorelin

Off-label · Grade C

Goals
muscle, sleep
Evidence
0 RCT / 2 animal / 0 in vitro
Routes
injectable-sc
WADA
S2
FDA
Not approved
Cancer caution
hard-stop
Typical dose
—
Half-life
CJC-1295 is a synthetic GHRH(1-29) analog with four amino acid substitutions that resist DPP-IV degradation, extending the base half-life from 7 minutes to approximately 30 minu…
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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