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Compound comparison

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L-Glutathione

Research chemical · Grade C

Goals
mitochondria, immune, longevity, beauty
Evidence
5 RCT / 0 animal / 0 in vitro
Routes
topical, oral
WADA
No
FDA
Not approved
Cancer caution
none
Typical dose
—
Half-life
Community practice: split doses morning and evening for GlyNAC given the ~6 hour plasma half-life of NAC
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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GHK (Basic)

Research chemical · Grade C

Goals
beauty, healing, longevity
Evidence
2 RCT / 4 animal / 5 in vitro
Routes
topical, scalp
WADA
No
FDA
Not approved
Cancer caution
hard-stop
Typical dose
—
Half-life
—
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
View full report →

Pinealon

Bioregulator · Grade C

Goals
cognition, sleep, longevity
Evidence
0 RCT / 1 animal / 2 in vitro
Routes
injectable-sc, injectable-im
WADA
No
FDA
Not approved
Cancer caution
caution
Typical dose
Community protocols commonly cite 2 mg daily for 10 days; evidence is extrapolated
Half-life
Unknown in humans; short peptide, likely rapid systemic clearance
Primary mechanism
Direct chromatin-interaction hypothesis
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Dasatinib + Quercetin

Off-label · Grade C

Goals
healing, longevity, immune
Evidence
0 RCT / 0 animal / 0 in vitro
Routes
oral
WADA
No
FDA
Not approved
Cancer caution
caution
Typical dose
—
Half-life
Half-life: 3-5 hours
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
View full report →