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Side by side

Compound comparison

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Semaglutide

FDA-approved · Grade A

Goals
weight-loss
Evidence
10 RCT / 1 animal / 0 in vitro
Routes
injectable-sc, oral
WADA
No
FDA
Approved
Cancer caution
none
Typical dose
—
Half-life
—
Primary mechanism
GLP-1 receptor agonism
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AOD-9604

Research chemical · Grade C

Goals
weight-loss, muscle, hormonal
Evidence
6 RCT / 4 animal / 3 in vitro
Routes
injectable-sc
WADA
S2
FDA
Not approved
Cancer caution
none
Typical dose
—
Half-life
—
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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Cagrilintide

Research chemical · Grade C

Goals
weight-loss, gut
Evidence
3 RCT / 1 animal / 0 in vitro
Routes
injectable-sc
WADA
No
FDA
Not approved
Cancer caution
caution
Typical dose
—
Half-life
—
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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Eloralintide

Research chemical · Grade C

Goals
weight-loss
Evidence
1 RCT / 1 animal / 1 in vitro
Routes
injectable-sc
WADA
No
FDA
Not approved
Cancer caution
none
Typical dose
—
Half-life
pharmacokinetics consistent with once-weekly dosing (half-life ~7 days from albumin-bound lipidated structure)
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
View full report →