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Side by side

Compound comparison

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SS-31

FDA-approved · Grade C

Goals
muscle, cognition, longevity, mitochondria
Evidence
3 RCT / 1 animal / 0 in vitro
Routes
injectable-sc
WADA
No
FDA
Approved
Cancer caution
caution
Typical dose
—
Half-life
SS-31 has a plasma half-life of approximately 30-60 minutes after SubQ injection
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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SS-20

Research chemical · Grade C

Goals
muscle, cognition, longevity, mitochondria
Evidence
0 RCT / 4 animal / 4 in vitro
Routes
injectable-sc
WADA
No
FDA
Not approved
Cancer caution
hard-stop
Typical dose
—
Half-life
Plasma half-life: estimated at 30-60 minutes after SubQ injection (comparable to SS-31)
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
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Humanin

Research chemical · Grade C

Goals
cognition, longevity, mitochondria
Evidence
0 RCT / 0 animal / 0 in vitro
Routes
injectable-sc
WADA
S4
FDA
Not approved
Cancer caution
hard-stop
Typical dose
—
Half-life
—
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
View full report →

J-147

Research chemical · Grade C

Goals
cognition, longevity, mitochondria
Evidence
1 RCT / 5 animal / 4 in vitro
Routes
oral
WADA
S4
FDA
Not approved
Cancer caution
caution
Typical dose
—
Half-life
—
Primary mechanism
Mechanism diagram showing the compound's primary signaling pathway and downstream effects.
View full report →